9 research outputs found
Planning level decision support for the selection of robust configurations of airport passenger buildings
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 1995.Includes bibliographical references (leaves 252-255).by Tom Svrcek.Ph.D
Presentations from the annual meeting of the MIT/Industry Cooperative research Program.
Caption titleMay 199
Presentations from the 1992 MIT/industry cooperative research program annual meeting
Cover titleMay 1992Includes bibliographical reference
Presentations from the MIT/Industry Cooperative Research Program : annual meeting, 1990
Statement of responsibility reads: Peter P. Belobaba; Catherine H. Bohutinsky; Anthony 0. Lee; Elizabeth L. Williamson; Amedeo R. Odoni, Stephan Kolitz and Mostafa Terrab; John Pararas; Robert W. Simpson; Tom Svrcek and Peter P. BelobabaJune 199
Presentations from the MIT/Industry Cooperative Research Program Annual Meeting, 1991
Cover titleMay 1991Includes bibliographical reference
Modeling airline group passenger demand for revenue optimization
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Civil Engineering, 1991.Includes bibliographical references (leaves 103-104).by Tom Svrcek.M.S
Hereditary diffuse gastric cancer: updated clinical practice guidelines
Hereditary diffuse gastric cancer (HDGC) is an autosomal dominant cancer syndrome that is characterised by a high prevalence of diffuse gastric cancer and lobular breast cancer. It is largely caused by inactivating germline mutations in the tumour suppressor gene CDH1, although pathogenic variants in CTNNA1 occur in a minority of families with HDGC. In this Policy Review, we present updated clinical practice guidelines for HDGC from the International Gastric Cancer Linkage Consortium (IGCLC), which recognise the emerging evidence of variability in gastric cancer risk between families with HDGC, the growing capability of endoscopic and histological surveillance in HDGC, and increased experience of managing long-term sequelae of total gastrectomy in young patients. To redress the balance between the accessibility, cost, and acceptance of genetic testing and the increased identification of pathogenic variant carriers, the HDGC genetic testing criteria have been relaxed, mainly through less restrictive age limits. Prophylactic total gastrectomy remains the recommended option for gastric cancer risk management in pathogenic CDH1 variant carriers. However, there is increasing confidence from the IGCLC that endoscopic surveillance in expert centres can be safely offered to patients who wish to postpone surgery, or to those whose risk of developing gastric cancer is not well defined.No Stomach for Cancer
DeGregorio Foundation
DD & DF Heads Charitable Trust
University of Otago
New Zealand Health Research Council Programme
17/610
Portuguese Foundation for Science and Technology
POCI-01-0145-FEDER-3016